In recent years, there has been an exponential growth in the amount of data due to digitalization. Many new algorithmic techniques have emerged to use the data for improved decision making. New companies are disrupting traditional markets by innovative digital business models, while established players are booking success by adapting their organisations and business relationships to the digital age. To respond adequately to the resulting increase in demand for expertise on how to transform data science into (business) value, we offer the MaastrichtMBA with a Business & Data Science specialisation. It connects Maastricht University’s expertise in the field of data science and its applications, with current and pressing business challenges from organisations and governmental institutions worldwide. Together we find new routes to navigate the complexity of this topic.